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Test Code AMLPC Amylase, Pancreatic Cyst Fluid

Additional Codes

EPIC Order Code LAB3863

Reporting Name

Amylase, Pancreatic Cyst

Useful For

Aiding in distinguishing between pseudocysts and other types of pancreatic cysts when used in conjunction with imaging studies, cytology, and other pancreatic cyst fluid tumor markers

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Pancreatic Cyst Fluid


Ordering Guidance


For other body fluid specimens (eg, peritoneal, pleural), order AMBF / Amylase, Body Fluid. Testing will be changed to AMBF if this test is ordered on any fluid other than pancreatic fluid.



Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Container/Tube: Plain vial

Specimen Volume: 1 mL

Additional Information: A minimum of 0.5 mL is required for testing; specimens less than 0.5 mL may be rejected.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Pancreatic Cyst Fluid Frozen (preferred) 30 days
  Ambient  7 days
  Refrigerated  7 days

Reference Values

An interpretive report will be provided.

Day(s) Performed

Monday through Saturday

CPT Code Information

82150

LOINC Code Information

Test ID Test Order Name Order LOINC Value
AMLPC Amylase, Pancreatic Cyst 48996-3

 

Result ID Test Result Name Result LOINC Value
AMYPC Amylase, Pancreatic Cyst 48996-3
SITE6 Site 39111-0

Interpretation

A pancreatic cyst fluid amylase concentration of less than 250 U/L indicates a low risk of a pseudocyst and is more consistent with cystic neoplasms such as mucinous cystic neoplasms (MCN), intraductal papillary mucinous neoplasm (IPMN), serous cystadenomas, cystic neuroendocrine tumor, and mucinous cystadenocarcinoma. High pancreatic cyst fluid amylase values are nonspecific and occur both in pseudocysts and some mucin-producing cystic neoplasms including MCN, IPMN, and mucinous cystadenocarcinoma.

 

In-house studies showed that using a cutoff value of less than 250 U/L to exclude a pseudocyst has 94% sensitivity and 42% specificity. Cysts with amylase levels of less than 250 U/L included 69% of adenocarcinomas, 31% of intraductal papillary mucinous neoplasia, 55% of mucinous cystadenomas, 64% serous cystadenomas, and 6% of pseudocysts.

Report Available

1 to 3 days

Reject Due To

Gross hemolysis Reject

Method Name

Substrate Kinetic

Forms

If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:

-Oncology Test Request (T729)

-Gastroenterology and Hepatology Test Request (T728)