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Test Code B2M Beta-2-Microglobulin, Serum

Additional Codes

CNE Order Code: B2 Microglob

Reporting Name

Beta-2-Microglobulin, S

Useful For

Prognosis assessment of multiple myeloma

 

Evaluation of renal tubular disorders

Testing Algorithm

For more information, see Multiple Myeloma: Laboratory Screening

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Serum


Specimen Required


Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 28 days
  Frozen  28 days
  Ambient  14 days

Reference Values

1.21-2.70 mcg/mL

Day(s) Performed

Monday through Friday

CPT Code Information

82232

LOINC Code Information

Test ID Test Order Name Order LOINC Value
B2M Beta-2-Microglobulin, S 1952-1

 

Result ID Test Result Name Result LOINC Value
B2M Beta-2-Microglobulin, S 1952-1

Interpretation

A serum beta-2-microglobulin (beta-2-M) value of less than 4 mcg/mL is a good prognostic factor in patients with multiple myeloma. In a study of pretreatment serum beta-2-M levels in 100 patients with myeloma, it was reported that the median survival of patients with values greater than 4 mcg/mL was 12 months, whereas median survival for patients with values less than 4 mcg/mL was 43 months.

Report Available

Same day/1 to 2 days

Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus OK

Method Name

Nephelometry

Forms

If not ordering electronically, complete, print, and send Renal Diagnostics Test Request (T830)