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Test Code BORDG Bordetella pertussis Antibody, IgG, Serum

Additional Codes

EPIC Order Code: LAB4232

Useful For

Diagnosis of recent infection with Bordetella pertussis in patients with symptoms consistent with whooping cough for 2 or more weeks

 

This test should not be used in neonates, young infants or in children between the ages of 4 to 7 years as the routine childhood vaccine schedule may interfere with result interpretation.

 

This test should not be used as a test of cure, to monitor response to treatment, or to determine vaccine status.

Method Name

Enzyme-Linked Immunosorbent Assay (ELISA)

Reporting Name

B. pertussis Ab, IgG, S

Specimen Type

Serum


Ordering Guidance


This test should be ordered in patients with 2 or more weeks of symptoms consistent with whooping cough. Nucleic acid amplification testing for Bordetella pertussis should be used in patients who have been symptomatic less than 2 weeks; order BPRPV / Bordetella pertussis and Bordetella parapertussis, Molecular Detection, PCR, Varies.



Specimen Required


Supplies: Sarstedt Aliquot Tube 5 mL (T914)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL Serum

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Specimen Minimum Volume

Serum: 0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 30 days
  Frozen  30 days

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus Reject
Heat-inactivated specimen Reject

Reference Values

≥100 IU/mL (Positive)

40-<100 IU/mL (Borderline)

<40 IU/mL (Negative)

Reference values apply to all ages.

Interpretation

Negative (<40 IU/mL): No IgG antibodies to pertussis toxin (PT) detected. Results may be falsely negative in patients with less than 2 weeks of symptoms.

 

Borderline (40-<100 IU/mL): Recommend follow-up testing in 10 to 14 days if clinically indicated.

 

Positive (≥100 IU/mL): IgG antibodies to PT detected. Results suggest recent infection with or recent vaccination against Bordetella pertussis.

Day(s) Performed

Thursday

Report Available

Same day/1 to 7 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

86615

LOINC Code Information

Test ID Test Order Name Order LOINC Value
BORDG B. pertussis Ab, IgG, S 42330-1

 

Result ID Test Result Name Result LOINC Value
BIGG B. pertussis IgG 29659-0
DEXBG B.pertussis Value 42330-1

Forms

If not ordering electronically, complete, print, and send Infectious Disease Serology Test Request (T916) with the specimen.