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HelpTest Code C1Q Complement C1q, Serum
Reporting Name
Complement C1q, SUseful For
Assessment of an undetectable total complement level
Diagnosing congenital C1 (first component of complement) deficiency
Diagnosing acquired deficiency of C1 inhibitor
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
SerumSpecimen Required
Patient Preparation: Fasting for 12 hours
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial
Specimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 28 days |
| Frozen | 28 days | |
| Ambient | 21 days |
Reference Values
12-22 mg/dL
Day(s) Performed
Monday through Friday
CPT Code Information
86160
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| C1Q | Complement C1q, S | 4478-4 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| C1Q | Complement C1q, S | 4478-4 |
Interpretation
An undetectable C1q in the presence of an absent total complement and normal C2, C3, and C4 suggests a congenital C1 (first component of complement) deficiency.
A low C1q in combination with a low C1 inhibitor and low C4 suggests an acquired C1 inhibitor deficiency.
Report Available
2 to 5 daysReject Due To
| Gross hemolysis | OK |
| Gross lipemia | Reject |
| Gross icterus | OK |
Method Name
Nephelometry