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HelpTest Code CAFF Caffeine, Serum
Additional Codes
CNE Order Code: Caffeine
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions:
1. Serum gel tubes should be centrifuged within 2 hours of collection.
2. Red-top tubes should be centrifuged and the serum aliquoted into a plastic vial within 2 hours of collection.
Useful For
Monitoring caffeine therapy in neonates
Assessing caffeine toxicity in neonates
Method Name
Enzyme Multiplied Immunoassay Technique (EMIT)
Reporting Name
Caffeine, SSpecimen Type
SerumSpecimen Minimum Volume
0.25 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Frozen (preferred) | 28 days | |
| Ambient | 72 hours | ||
| Refrigerated | 72 hours |
Reject Due To
| Gross hemolysis | Reject |
Reference Values
Therapeutic: 8.0-20.0 mcg/mL
Critical value: ≥30.0 mcg/mL
Interpretation
Optimal pharmacologic response occurs when the serum level is in the range of 8.0 to 20.0 mcg/mL.
Toxicity in neonates and adults may be seen when the serum level is above 20.0 mcg/mL.
Day(s) Performed
Monday through Saturday
Report Available
Same day/1 to 2 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
80155
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| CAFF | Caffeine, S | In Process |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 8754 | Caffeine, S | 3422-3 |
Forms
If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.