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HelpTest Code CIFST Cutaneous Immunofluorescence Antibodies Titer, IgG, Serum
Specimen Required
Only orderable as a reflex. For more information see CIFS / Cutaneous Immunofluorescence Antibodies, IgG and IgG4, Serum.
Collection Container/Tube:
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 2 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Useful For
Confirmation of positive IgG anti-cell surface (CS) and anti-basement membrane zone (BMZ) antibodies.
Method Name
Only orderable as a reflex. For more information see CIFS / Cutaneous Immunofluorescence Antibodies, IgG and IgG4, Serum.
Indirect Immunofluorescence Assay (IFA)
Reporting Name
CIFS Titer, IgG, SSpecimen Type
SerumSpecimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 14 days |
| Frozen | 30 days | |
| Ambient | 14 days |
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
Reference Values
Only orderable as a reflex. For more information see CIFS / Cutaneous Immunofluorescence Antibodies, IgG and IgG4, Serum.
Negative in normal individuals
Interpretation
Indirect immunofluorescence (IF) testing may be diagnostic when histologic or direct IF studies are only suggestive, nonspecific, or negative.
Anti-cell surface antibodies correlate with a diagnosis of pemphigus.
Anti-basement membrane zone antibodies correlate with a diagnosis of bullous pemphigoid, cicatricial pemphigoid, epidermolysis bullosa acquisita, or bullous eruption of lupus erythematosus.
Day(s) Performed
Monday through Friday
Report Available
2 to 7 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
88350
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| CIFST | CIFS Titer, IgG, S | 104835-4 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 622323 | Cell Surface Ab Titer, IgG | 104831-3 |
| 622324 | Basement Membrane Titer, IgG | 104836-2 |
| 622325 | Other | 48767-8 |