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Test Code CRTHT Double-Stranded DNA (dsDNA) IgG Antibodies, Crithidia luciliae Immunofluorescence Titer, Serum (Non-Orderable)


Specimen Required


Only orderable as a reflex. For more information see CRTHS / Double-Stranded DNA (dsDNA) IgG Antibodies, Crithidia luciliae Immunofluorescence Screen, Serum.

 

Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.8 mL Serum

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Useful For

Only orderable as a reflex. For more information see CRTHS / Double-Stranded DNA (dsDNA) IgG Antibodies, Crithidia luciliae Immunofluorescence Screen, Serum.

 

Antibody titer testing for antibodies to double-stranded DNA using the Crithidia luciliae indirect immunofluorescence test is part of the evaluation of patients with clinical features of systemic lupus erythematosus (SLE) or at-risk for disease

 

This test should not be used independently for the diagnosis and management of patients with SLE.

Method Name

Only orderable as a reflex. For more information see CRTHS / Double-Stranded DNA (dsDNA) IgG Antibodies, Crithidia luciliae Immunofluorescence Screen, Serum.

 

Indirect Immunofluorescence Assay (IFA)

Reporting Name

dsDNA Ab IFA Titer, IgG, S

Specimen Type

Serum

Specimen Minimum Volume

See Specimen Required

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 7 days
  Frozen  21 days

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus OK
Heat-treated Reject

Reference Values

Only orderable as a reflex. For more information see CRTHS / Double-Stranded DNA (dsDNA) IgG Antibodies, Crithidia luciliae Immunofluorescence Screen, Serum.

 

Negative (<1:10)

Interpretation

The presence of IgG antibodies to double-stranded DNA detected using the Crithidia luciliae indirect immunofluorescence test is highly specific for systemic lupus erythematosus (SLE) with moderate sensitivity.

 

A negative result does not exclude a diagnosis of SLE.

Day(s) Performed

Monday through Friday

Report Available

2 to 4 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

86256

LOINC Code Information

Test ID Test Order Name Order LOINC Value
CRTHT dsDNA Ab IFA Titer, IgG, S 58466-4

 

Result ID Test Result Name Result LOINC Value
623427 dsDNA Ab IFA Titer, IgG, S 58466-4