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Test Code Celiac Celiac Disease Screen

Important Note

Includes:  Tissue Transglutaminase Antibodies (TTG IgA and IgG) and Gliadin Antibodies (IgA and IgG Deamidated). Equivocal results for TTG IgA will be reflexed to Endomysial  Antibody testing.

Specimen Type

Blood

Minimum Volume

1.0 mL

Container

Plain Red
Serum/Refrigerate

Turnaround Time

Batch tested Tuesday, Wednesday and Friday.

Testing days subject to change based on volume

Methodology

Fluorescent Enzymatic Immunoassay

TTG IgA Reference Range

≤6.9 unit/mL Negative

Antibody results should not be used alone for diagnosis and must be interpreted in light of clinical manifestations and other test results.
The presence of the tissue transglutaminase (tTG) IgA antibody is associated with gluten-sensitive enteropathies such as celiac disease and dermatitis herpetiformis.

TTG IgG Reference Range

≤6.9 unit/mL Negative

Antibody results should not be used alone for diagnosis and must be interpreted in light of clinical manifestations and other test results. The tTG IgG assay may aid in the diagnosis of gluten-sensitivity enteropathy (i.e., celiac disease, dermatitis herpetiformis) in tTG IgA negative patients with confirmed IgA deficiency.

 

Gliadin IgA Deaminated Reference Range

≤6.9 unit/mL Negative

Antibody results should not be used alone for diagnosis and must be interpreted in light of clinical manifestations and other test results.
Positive test results for deamidated gliadin IgG antibodies are consistent with a diagnosis of celiac disease. A decrease in the concentrations of deamidated gliadin IgG antibodies may begin after initiation of a gluten-free diet and could indicate a response to therapy.

 

Giadin IgG Deaminated Reference Range

≤6.9 unit/mL Negative

Antibody results should not be used alone for diagnosis and must be interpreted in light of clinical manifestations and other test results.
Positive test results for deamidated gliadin IgG antibodies are consistent with a diagnosis of celiac disease. A decrease in the concentrations of deamidated gliadin IgG antibodies may begin after initiation of a gluten-free diet and could indicate a response to therapy.

 

CPT

86258x2

86364x2