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HelpTest Code EZNT8 Zinc Transporter 8 (ZnT8) Antibody, Serum
Useful For
Clinical distinction of type 1 from type 2 diabetes mellitus
Identification of individuals at risk of type 1 diabetes (including high-risk relatives of patients with diabetes, and those with gestational diabetes)
Prediction of future need for insulin treatment in adult-onset diabetic patients
Method Name
Enzyme-Linked Immunosorbent Assay (ELISA)
Reporting Name
ZnT8 Ab, SSpecimen Type
SerumSpecimen Required
Collection Container/Tube:
Preferred: Red top
Acceptable: Serum gel
Submission Container/Tube: Plastic vial
Specimen Volume: 2 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Specimen Minimum Volume
1 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 28 days | |
| Frozen | 28 days | ||
| Ambient | 72 hours |
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
Reference Values
<15.0 U/mL
Interpretation
Seropositivity for ZnT8 autoantibody (≥15 IU/mL) is supportive of:
-A diagnosis of type 1 diabetes
-A high risk for future development of diabetes
-A current or future need for insulin therapy in patients with diabetes
Day(s) Performed
Tuesday, Thursday
Report Available
3 to 7 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
86341
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| EZNT8 | ZnT8 Ab, S | 76651-9 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 64926 | ZnT8 Ab, S | 76651-9 |