-1651085832.png){kind=logo}
Home
HelpTest Code HYDMS Hydromorphone, Serum
Ordering Guidance
This test should only be ordered by healthcare professionals to monitor patients who have been prescribed hydromorphone.
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube: Red top (Serum gel/SST are not acceptable)
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL serum
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Useful For
Monitoring therapeutic efficacy/compliance in serum specimens of patients who are prescribed hydromorphone
Special Instructions
Method Name
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Reporting Name
Hydromorphone, SSpecimen Type
Serum RedSpecimen Minimum Volume
Serum: 0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum Red | Refrigerated (preferred) | 14 days |
| Frozen | 28 days | |
| Ambient | 24 hours |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | OK |
| Gross icterus | OK |
Reference Values
Therapeutic range: 1.0-30 ng/mL
Cutoff concentration: 1.0 ng/mL
Interpretation
Clinically, the presence of hydromorphone in serum can be used to verify adherence or compliance to prescribed opioids, and discourage drug misuse, abuse, and diversion.
When used as sole therapy, the adult therapeutic range suggested by the literature is 1.0-30 ng/mL but must be interpreted alongside other clinical features/test results, symptoms, collection time since last dosage was taken, and signs of abuse/misuse.
Day(s) Performed
Wednesday
Report Available
2 to 9 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
G0480
80361 (if appropriate for select payers)
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| HYDMS | Hydromorphone, S | 12787-8 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 623455 | Hydromorphone - Free | 12787-8 |