Notes

Absence of detectable VCA IgM antibodies. If exposure to Epstein-Barr is suspected despite a negative finding, a second sample should be collected and tested no less than one to two weeks later.

Specific IgM antibodies are usually detected in patients with recent primary infection and may be found in patients with reactivated infections. Other EBV serology assays should be performed to confirm EBV-associated infectious mononucleosis.

The equivocal sample should be repeated tested. In case the result remains in this range after repeat testing, a second sample should be collected and tested no less than one or two weeks later.