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HelpTest Code LAGGN Granulocyte Antibody Screen, Serum
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube: Red top (serum gel/SST are not acceptable)
Submission Container/Tube: Plastic vial
Specimen Volume: 1.5 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Additional Information: Only a specimen collected before a transfusion reaction is acceptable.
Useful For
Work-up of individuals with autoimmune neutropenia
Work-up of individuals having febrile nonhemolytic transfusion reactions
Work-up for alloimmune neonatal neutropenia
This test is not useful for the diagnosis of neutropenia due to marrow suppression by drugs or tumors.
Method Name
Flow Cytometry/Agglutination
Reporting Name
Granulocyte Ab Screen, SSpecimen Type
Serum RedSpecimen Minimum Volume
0.3 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum Red | Refrigerated (preferred) | 30 days |
| Frozen | 365 days | |
| Ambient | 7 days |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | OK |
| Gross icterus | OK |
Reference Values
Not applicable
Interpretation
A positive result can be due to anti-granulocyte antibodies and anti-human leukocyte antigen antibodies.
This test cannot distinguish between allo- or autoantibodies, nor can it determine the specificity of the detected antibody. Results should be correlated to clinical history.
Day(s) Performed
Tuesday, Thursday
Report Available
7 to 15 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
86021 x2
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| LAGGN | Granulocyte Ab Screen, S | 105285-1 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| LAGG2 | GIFT/GAT Interpretation | 105288-5 |
| LAGG3 | GIFT Result | 105286-9 |
| LAGG4 | GAT Result | 105287-7 |