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HelpTest Code MYCO Mycoplasma pneumoniae Antibodies, IgG and IgM, Serum
Additional Codes
CNE Order Code: Mycopl Ab
Ordering Guidance
Detection of IgM or IgG class antibodies to Mycoplasma pneumoniae provides exposure information. The preferred method of diagnosis of acute M pneumoniae infection is by molecular detection; order MPRP / Mycoplasma pneumoniae, Molecular Detection, PCR, Varies.
Specimen Required
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Useful For
Screening for recent or past exposure to Mycoplasma pneumoniae
This test should not be used as a screening procedure for the general population.
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| MYCOG | M. pneumoniae Ab, IgG, S | No | Yes |
| MYCOM | M. pneumoniae Ab, IgM, S | No | Yes |
| MYCON | M. pneumoniae Ab Interpretation | No | Yes |
Reflex Tests
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| MMYCO | M. pneumoniae Ab, IgM, S by IFA | No | No |
Testing Algorithm
If the Mycoplasma pneumoniae IgM result is reactive or equivocal, then M pneumoniae IgM by indirect immunofluorescence assay will be performed at an additional charge.
Method Name
MYCOG, MYCOM: Enzyme Immunoassay (EIA)
MMYCO: Indirect Immunofluorescence Assay (IFA)
MYCON: Interpretation
Reporting Name
M. pneumoniae Ab, IgG and IgM, SSpecimen Type
SerumSpecimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 14 days | |
| Frozen | 14 days |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Heat inactivated specimen | Reject |
Reference Values
IgG: Negative
IgM: Negative
IgM by indirect immunofluorescence: Negative
Interpretation
|
IgG ELISA result |
IgM ELISA result |
Interpretation |
|
Positive |
Negative |
Results suggest past exposure. |
|
Positive
|
Reactive |
Prior exposure to Mycoplasma pneumoniae detected. Confirmatory testing for IgM to M pneumonia will be performed by an immunofluorescence assay. |
|
Equivocal |
||
|
Negative |
Negative |
No antibodies to M pneumoniae detected. Acute infection cannot be ruled out as antibody levels may be below the limit of detection. If clinically indicated, a second serum should be submitted in 14 to 21 days. |
|
Negative |
Reactive |
No prior exposure to Mycoplasma pneumoniae. Confirmatory testing for IgM to M pneumonia will be performed by an immunofluorescence assay.. |
|
Equivocal |
||
|
Equivocal |
Negative |
Recommend follow-up testing in 10 to 14 days if clinically indicated. |
|
Reactive |
Confirmatory testing for IgM to M pneumonia will be performed by an immunofluorescence assay. |
|
|
Equivocal |
ELISA = Enzyme-linked immunosorbent assay
Day(s) Performed
Monday through Friday
Report Available
Same day/1 to 3 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
86738 x 2-Mycoplasma pneumoniae by EIA
86738-Mycoplasma pneumoniae by indirect IFA (if appropriate)
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| MYCO | M. pneumoniae Ab, IgG and IgM, S | 58733-7 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| MYCOG | M. pneumoniae Ab, IgG, S | 45224-3 |
| MYCOM | M. pneumoniae Ab, IgM, S | 5257-1 |
| MYCON | M. pneumoniae Ab Interpretation | 69048-7 |
Forms
If not ordering electronically, complete, print, and send Infectious Disease Serology Test Request (T916) with the specimen.