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HelpTest Code NMRLP Nuclear Magnetic Resonance Lipoprotein Profile, Serum
Specimen Required
Patient Preparation:
1. Fasting overnight (12-14 hours) is required. On night before examination, evening meal should be eaten before 6 p.m. and should contain no fatty foods.
2. Patient must not consume any alcohol for 24 hours before the specimen is collected.
Collection Container/Tube: Red top (serum gel/SST are not acceptable)
Submission Container/Tube: Plastic vial
Specimen Volume: 1.5 mL
Collection Instructions:
1. Allow isopropyl alcohol (from phlebotomy site prep) to dry thoroughly before venipuncture.
2. Centrifuge and aliquot serum into a plastic vial.
Useful For
Assessment and management of a patient's risk for atherosclerotic cardiovascular disease
Identifying residual risk that may be present in some patients on cholesterol targeting treatment
Method Name
Nuclear Magnetic Resonance (NMR)
Reporting Name
NMR Lipoprotein Profile, SSpecimen Type
Serum RedSpecimen Minimum Volume
1 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum Red | Refrigerated (preferred) | 7 days | |
| Frozen | 14 days | ||
| Ambient | 8 hours |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | Reject |
Reference Values
≥18 years:
LDL Particles:
Desirable: <1,000 nmol/L
Above Desirable: 1,000-1,299 nmol/L
Borderline high: 1,300-1,599 nmol/L
High: 1,600-2,000 nmol/L
Very high: ≥2,000 nmol/L
HDL Particles:
Male: >30 mcmol/L
Female: >35 mcmol/L
LDL Cholesterol (NMR):
Desirable: <100 mg/dL
Above Desirable: 100-129 mg/dL
Borderline high: 130-159 mg/dL
High: 160-189 mg/dL
Very high: ≥190 mg/dL
Reference values have not been established for patients younger than 18 years of age.
Interpretation
Elevated concentrations of low-density lipoprotein particle (LDL-P) are associated with increased risk of atherosclerotic cardiovascular disease.
LDL-P is a more accurate indicator of risk when LDL cholesterol is discordantly low.
Lower concentrations of high-density lipoprotein particle are associated with increased risk of atherosclerotic cardiovascular disease.
Day(s) Performed
Tuesday,Friday
Report Available
2 to 7 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
83704
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| NMRLP | NMR Lipoprotein Profile, S | In Process |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 606167 | LDL Particles, S | 54434-6 |
| 606168 | HDL Particles, S | 49748-7 |
| 606169 | LDL Cholesterol (NMR), S | 2089-1 |
Forms
If not ordering electronically, complete, print, and send a Cardiovascular Test Request Form (T724) with the specimen.