-1651085832.png){kind=logo}
Home
HelpTest Code PAI1 Plasminogen Activator Inhibitor Antigen, Plasma
Specimen Required
Specimen Type: Platelet-poor plasma
Collection Container/Tube: Light-blue top (3.2% sodium citrate)
Submission Container/Tube: Plastic vial (polypropylene preferred)
Specimen Volume: 1 mL
Collection Instructions:
1. For complete instructions, see Coagulation Guidelines for Specimen Handling and Processing.
2. Centrifuge, transfer all plasma into a plastic vial, and centrifuge plasma again.
3. Aliquot plasma into a plastic vial leaving 0.25 mL in the bottom of centrifuged vial.
4. Freeze plasma immediately (no longer than 4 hours after collection) at -20° C or ideally, at or below -40° C.
Specimen Stability Information: Frozen 2 years
Additional Information:
1. Double-centrifuged specimen is critical for accurate results as platelet contamination may cause spurious results.
2. Each coagulation assay requested should have its own vial.
Forms
If not ordering electronically, complete, print, and send a Coagulation Test Request (T753) with the specimen.
Useful For
Identification of heredity elevation or deficiency of plasminogen activator inhibitor type 1
Determination of risk for veno-occlusive disease associated with bone marrow transplantation
Differential diagnosis of impaired fibrinolysis
Prognostic marker of occurrence or recurrence of thrombosis
Special Instructions
Method Name
Enzyme-Linked Immunosorbent Assay (ELISA)
Reporting Name
PAI-1 Ag, PSpecimen Type
Plasma Na CitSpecimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Plasma Na Cit | Frozen | ||
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | Reject |
Reference Values
3.0-72.0 ng/mL
Interpretation
Increased levels of plasminogen activator inhibitor type 1 (PAI-1) are associated with a predisposition to thrombosis.
Decreased or absent levels of detectable functional PAI-1 will result in a life-long bleeding diathesis.
Day(s) Performed
Wednesday
Report Available
7 to 12 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
85415
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| PAI1 | PAI-1 Ag, P | 22758-7 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 86083 | PAI-1 Ag, P | 22758-7 |