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Test Code SPNC Streptococcus pneumoniae Antigen, Spinal Fluid

Reporting Name

Streptococcus pneumoniae Ag, CSF

Useful For

Rapid diagnosis of pneumococcal meningitis

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

CSF


Additional Testing Requirements


According to the College of American Pathologists (CAP, IMM.41830), cerebrospinal fluid (CSF) samples collected to make an initial diagnosis and submitted for detection of Streptococcus pneumoniae antigen testing should also be submitted for routine bacterial culture. Mayo Clinic Laboratories recommends that CSF bacterial cultures be performed at the originating site.



Specimen Required


Container/Tube: Sterile vial

Specimen Volume: 1 mL

Collection Instructions: Submit specimen collected in vial 2, if possible. If not possible, note which vial from which the aliquot was obtained.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
CSF Refrigerated (preferred) 14 days
  Frozen  14 days

Reference Values

Negative

Reference values apply to all ages.

Day(s) Performed

Monday through Sunday

CPT Code Information

87899

LOINC Code Information

Test ID Test Order Name Order LOINC Value
SPNC Streptococcus pneumoniae Ag, CSF 20489-1

 

Result ID Test Result Name Result LOINC Value
31667 Streptococcus pneumoniae Ag, CSF 20489-1

Interpretation

A positive result supports a diagnosis of pneumococcal meningitis.

 

A negative result suggests that pneumococcal antigen is absent in the cerebrospinal fluid (CSF). However, infection due to Streptococcus pneumoniae cannot be ruled out since the antigen present in the specimen may be below the lower limit of detection of the test.

 

If pneumococcal meningitis is suspected, bacterial culture and Gram stain analysis on CSF should be performed.

Report Available

Same day/1 day

Reject Due To

Gross hemolysis OK
Gross lipemia OK

Method Name

Immunochromatographic Membrane Assay

Forms

If not ordering electronically, complete, print, and send Infectious Disease Serology Test Request (T916) with the specimen.