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Mayo Clinic Laboratories

Test Code Smith AB Smith Antibody

Specimen Type

Blood

Minimum Volume

1.0 mL

Container

Plain Red
Serum/Refrigerate

Methodology

Fluorescent Enzymatic Immunoassay

Turnaround Time

Batch tested Tuesday, Wednesday and Friday.

Testing days subject to change based on volume

Reference Range

≤6.9 unit/mL Negative

Notes

Antibody results should not be used alone for diagnosis and must be interpreted in light of clinical manifestations and other test results.
Smith antibodies offer a highly specific, but comparatively insensitive, clinical marker for SLE. Their presence constitutes one of the revised American College of Rheumatology criteria, even though their overall presence ranges from 20% to 30% in SLE.

CPT Code

86235