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HelpTest Code TOBTA Tobramycin, Trough, Serum
Additional Codes
CNE Order Code: Tobra Trough
Useful For
Monitoring adequate clearance of tobramycin near the end of a dosing cycle
Method Name
Immunoassay
Reporting Name
Tobramycin, Trough, SSpecimen Type
SerumSpecimen Required
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions:
1. Draw blood no more than 30 minutes before next scheduled dose.
2. Serum gel tubes should be centrifuged within 2 hours of collection.
3. Red-top tubes should be centrifuged, and the serum aliquoted into a plastic vial within 2 hours of collection.
Specimen Minimum Volume
0.25 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 7 days | |
| Frozen | 28 days | ||
| Ambient | 72 hours |
Reject Due To
| Gross hemolysis | Reject |
Reference Values
Therapeutic: <2.0 mcg/mL
Toxic: >2.0 mcg/mL
Interpretation
Goal levels depend on the type of infection being treated. Goal trough levels should be below 2.0 mcg/mL for conventional (nonpulse) dosing. Prolonged exposure to trough levels exceeding 2.0 mcg/mL may lead to toxicity.
Day(s) Performed
Monday through Sunday
Report Available
Same day/1 to 2 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
80200
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| TOBTA | Tobramycin, Trough, S | 4059-2 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| TOBTA | Tobramycin, Trough, S | 4059-2 |
Forms
If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.