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HelpTest Code TPBF Protein, Total, Body Fluid
Additional Codes
CNE Order Code: BF Protein
Reporting Name
Protein, Total, BFPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
Body FluidOrdering Guidance
For protein measurement in spinal fluid specimens, order TPSF / Protein, Total, Spinal Fluid. Testing will be changed to TPSF if this test is ordered on that specimen type.
Necessary Information
1. Date and time of collection are required.
2. Specimen source is required.
Specimen Required
Specimen Type: Body fluid
Preferred Source:
-Peritoneal fluid (peritoneal, abdominal, ascites, paracentesis)
-Pleural fluid (pleural, chest, thoracentesis)
-Drain fluid (drainage, JP drain)
-Pericardial
Acceptable Source: Write in source name with source location (if appropriate)
Collection Container/Tube: Sterile container
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions:
1. Centrifuge to remove any cellular material and transfer into a plastic vial.
2. Indicate the specimen source and source location on label.
Specimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Body Fluid | Refrigerated (preferred) | 7 days | |
| Frozen | 30 days | ||
| Ambient | 24 hours |
Reference Values
An interpretive report will be provided.
Day(s) Performed
Monday through Sunday
CPT Code Information
84157
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| TPBF | Protein, Total, BF | 2881-1 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| TPBF1 | Protein, Total, BF | 2881-1 |
| FLD23 | Fluid Type, Protein, Total | 14725-6 |
Report Available
Same day/1 to 2 daysReject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | Reject |
| Anticoagulant or additive Breast milk Nasal secretions Gastric secretions Bronchoalveolar lavage (BAL) or bronchial washings Colostomy/ostomy Feces Cerebrospinal fluid Saliva Sputum Urine Vitreous fluid |
Reject |
Method Name
Colorimetric
Useful For
Identification of exudative pleural effusions
Differentiating hepatic from other causes of ascites that have elevated serum ascites albumin gradient using peritoneal fluid
Interpretation
A pleural fluid total protein to serum total protein ratio of above 0.5 is most consistent with exudative effusion.(2,5)
A peritoneal fluid total protein of above 2.5 g/dL in patients with a high serum ascites albumin gradient can be caused by heart failure. A peritoneal fluid total protein of over 1.0 g/dL helps to differentiate secondary from spontaneous bacterial peritonitis in conjunction with other laboratory, imaging, and clinical findings.(6,7,8)
The usefulness of measuring total protein in pericardial fluid is not well documented. Results may be interpreted in conjunction with serum or plasma total protein concentrations.
The usefulness of measuring total protein in synovial fluid is limited as it has poor sensitivity and specificity for differentiating inflammatory vs noninflammatory causes and should be interpreted in conjunction with other clinical findings.(9)
All other fluids: Total protein may be used to differentiate transudative from exudative effusions. The decision limits are not well defined in fluids other than pleural fluid and should be interpreted in conjunction with other clinical findings.(10)
Forms
If not ordering electronically, complete, print, and send a Renal Diagnostics Test Request (T830) with the specimen.