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HelpTest Code TULAB Francisella tularensis Antibody, IgM and IgG, ELISA, Serum
Additional Codes
CNE Order Code: TularemiaAb
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.6 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Useful For
Aiding in the diagnosis of tularemia caused by Francisella tularensis
This test should not be used as a test of cure as it is not quantitative. Patients may remain seropositive for months to years following resolution of disease.
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| TULM | F. tularensis Ab, IgM ELISA, S | No | Yes |
| TULG | F. tularensis Ab, IgG ELISA, S | No | Yes |
| TULI | F. tularensis Interpretation | No | Yes |
Method Name
Enzyme-Linked Immunosorbent Assay (ELISA)
Reporting Name
F. tularensis Ab, IgM/IgG ELISA, SSpecimen Type
SerumSpecimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 7 days | |
| Frozen | 30 days |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | Reject |
| Heat inactivated specimen | Reject |
Reference Values
Negative
Reference values apply to all ages.
Interpretation
|
IgM result |
IgG result |
Interpretation |
|
Negative |
Negative |
No antibodies to Francisella tularensis detected. Antibody response may be negative in samples collected too soon following infection/exposure. Repeat testing on a new sample in 1 to 2 weeks if clinically indicated. |
|
Positive |
Negative |
IgM class antibodies to F tularensis detected, suggesting current or recent infection. Repeat testing in 1 to 2 weeks to detect seroconversion of IgG may be considered to confirm the diagnosis. |
|
Positive |
Borderline |
|
|
Borderline |
Negative |
Questionable presence of IgM antibodies to F tularensis. Consider repeat testing in 1 to 2 weeks. |
|
Borderline |
Positive |
IgG class antibodies to F tularensis detected suggesting recent or past infection. Clinical correlation alongside presentation, exposure history and other laboratory findings required. |
|
Borderline |
Borderline |
Questionable presence of IgM and IgG class antibodies to F tularensis. Consider repeat testing in 1 to 2 weeks. |
|
Positive |
Positive |
IgM and IgG class antibodies to F tularensis detected suggesting current, recent or past infection. Cross-reactions may occur in patients with a current or prior Brucella infection. Clinical correlation alongside presentation, exposure history and other laboratory findings required. |
|
Negative |
Positive |
IgG class antibodies to F tularensis detected suggesting recent or past infection. Clinical correlation alongside presentation, exposure history and other laboratory findings required. |
|
Negative |
Borderline |
Questionable presence of IgG antibodies to F tularensis. Consider repeat testing in 1 to 2 weeks. |
Day(s) Performed
Tuesday, Thursday
Report Available
Same day/1 to 7 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
86668 x 2
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| TULAB | F. tularensis Ab, IgM/IgG ELISA, S | 93715-1 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| TULM | F. tularensis Ab, IgM ELISA, S | 93716-9 |
| TULG | F. tularensis Ab, IgG ELISA, S | 93717-7 |
| TULI | F. tularensis Interpretation | 93718-5 |
Forms
If not ordering electronically, complete, print, and send Infectious Disease Serology Test Request (T916) with the specimen.