Sign in →

Test Code UHBAG Histoplasma and Blastomyces Antigen, Enzyme Immunoassay, Urine


Specimen Required


Supplies: Sarstedt Aliquot tube, 5 mL (T914)

Container/Tube: Plastic vial

Specimen Volume: 3 mL

Collection Instructions:

1. Collect a random urine specimen, with no preservative.

2. Do not centrifuge to remove particulates.


Useful For

Diagnosing Histoplasma capsulatum or Blastomyces dermatitidis infection without differentiation between the organisms

 

Monitor antigen levels following initiation of antifungal treatment

Method Name

Enzyme Immunoassay (EIA)

Reporting Name

Histoplasma/Blastomyces Ag, EIA, U

Specimen Type

Urine

Specimen Minimum Volume

2.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated (preferred) 14 days
  Frozen  28 days
  Ambient  7 days

Reject Due To

Gross hemolysis Reject
Turbid
Colored
Reject

Reference Values

Histoplasma/Blastomyces Antigen Result:

Not Detected

 

Histoplasma/Blastomyces Antigen Value:

Not Detected: 0.0 ng/mL

Detected: <1.3 ng/mL

Detected: 1.3-20.0 ng/mL

Detected: >20.0 ng/mL

 

Reference values apply to all ages.

Interpretation

Not detected:

No antigen from Histoplasma or Blastomyces detected. False-negative results may occur depending on extent of disease or site of infection. Repeat testing on a new specimen if clinically indicated.

 

Detected:

Antigen from Histoplasma or Blastomyces (unable to differentiate) was detected, below the limit of quantification (<1.3 ng/mL). Result should be correlated with clinical presentation, exposure history, and other diagnostic procedures, including culture, serology, histopathology, and radiographic findings to aid in the differentiation between histoplasmosis or blastomycosis.

 

Detected:

Antigen from Histoplasma or Blastomyces (unable to differentiate) detected. Result should be correlated with clinical presentation, exposure history, and other diagnostic procedures, including culture, serology, histopathology, and radiographic findings, to aid in the differentiation between histoplasmosis and blastomycosis.

 

Detected:

Antigen from Histoplasma or Blastomyces (unable to differentiate) detected, above the limit of quantification (>20.0 ng/mL). Result should be correlated with clinical presentation, exposure history, and other diagnostic procedures, including culture, serology, histopathology, and radiographic findings, to aid in the differentiation between histoplasmosis or blastomycosis.

Day(s) Performed

Monday through Sunday

Report Available

Same day/1 to 3 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

87449

LOINC Code Information

Test ID Test Order Name Order LOINC Value
UHBAG Histoplasma/Blastomyces Ag, EIA, U 105123-4

 

Result ID Test Result Name Result LOINC Value
UHBAR Histoplasma/Blastomyces Ag Result 104871-9
DEXBH Histoplasma/Blastomyces Ag Value 104872-7