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HelpTest Code WAGDR Alpha Globin Cluster Locus Deletion/Duplication, Blood
Ordering Guidance
Sequence variants, other than the alpha T-Saudi and hemoglobin Constant Spring alterations, are not detected by this assay. For detection of single point and other nondeletion variants, order WASEQ / Alpha Globin Gene Sequencing, Varies, if clinically indicated.
Shipping Instructions
Specimen Required
Patient Preparation: A previous bone marrow transplant from an allogeneic donor will interfere with testing. For instructions for testing patients who have received a bone marrow transplant, call 800-533-1710.
Specimen Type: Whole blood
Container/Tube:
Preferred: Lavender top (EDTA)
Acceptable: Yellow top (ACD)
Specimen Volume: 3 mL
Collection Instructions:
1. Invert several times to mix blood.
2. Send whole blood specimen in original tube. Do not aliquot.
Forms
1. New York Clients-Informed consent is required. Document on the request form or electronic order that a copy is on file. The following documents are available in Special Instructions:
-Informed Consent for Genetic Testing (T576)
-Informed Consent for Genetic Testing-Spanish (T826)
2. Molecular Genetics: Congenital Inherited Diseases Patient Information (T521)
Useful For
Diagnosis of alpha-thalassemia
Carrier screening for individuals from high-risk populations for alpha-thalassemia
This test is not useful for diagnosis or confirmation of beta-thalassemia or hemoglobinopathies.
Special Instructions
Method Name
Dosage Analysis by Polymerase Chain Reaction (PCR)/Quantitative Polymerase Chain Reaction (qPCR)/Multiplex Ligation-Dependent Probe Amplification (MLPA)
Reporting Name
Alpha Globin Clustr Locus Del/Dup,BSpecimen Type
VariesSpecimen Minimum Volume
Blood: 1 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Varies | Varies | |
Reject Due To
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.Reference Values
An interpretive report will be provided.
Interpretation
The interpretive report includes an overview of the findings as well as the associated clinical significance.
Day(s) Performed
Varies
Report Available
9 to 13 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
81269
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| WAGDR | Alpha Globin Clustr Locus Del/Dup,B | 90040-7 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 621362 | Result Summary | 50397-9 |
| 621363 | Result | 82939-0 |
| 621364 | Interpretation | 69047-9 |
| 621365 | Additional Information | 48767-8 |
| 621366 | Specimen | 31208-2 |
| 621367 | Source | 31208-2 |
| 621368 | Method | 85069-3 |
| 621804 | Disclaimer | 62364-5 |
| 621369 | Released By | 18771-6 |