Sign in →

Test Code ZNUCR Zinc/Creatinine Ratio, Random, Urine


Ordering Guidance


The use of blood testing is recommended for children younger than 10 years. Order ZN_S / Zinc, Serum.



Specimen Required


Patient Preparation: High concentrations of barium are known to interfere with most metal tests. If barium-containing contrast media has been administered, the specimen should not be collected for at least 96 hours.

Supplies: Urine Tubes, 10 mL (T068)

Collection Container/Tube: Clean, plastic urine collection container with no metal cap or glued insert

Submission Container/Tube: Plastic urine tube or clean, plastic aliquot container with no metal cap or glued insert

Specimen Volume: 3 mL

Collection Instructions:

1. Collect a random urine specimen.

2. See Metals Analysis Specimen Collection and Transport for complete instructions.


Useful For

Identifying the cause of abnormal serum zinc concentrations using a random urine specimen

Profile Information

Test ID Reporting Name Available Separately Always Performed
ZNCU Zinc/Creat Ratio, U No Yes
CRETR Creatinine, Random, U No Yes

Method Name

ZNCU: Triple-Quadrupole Inductively-Coupled Plasma Mass Spectrometry (ICP-MS/MS)

CRETR: Enzymatic Colorimetric Assay

Reporting Name

Zinc/Creat Ratio, Random, U

Specimen Type

Urine

Specimen Minimum Volume

2 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated (preferred) 28 days
  Frozen  28 days
  Ambient  14 days

Reject Due To

  All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Reference Values

ZINC/CREATININE:

0-17 years: Not established

≥18 years: 89-910 mcg/g creatinine

 

CREATITINE:

≥18 years old: 16-326 mg/dL

Reference values have not been established for patients who are younger than 18 years.

Interpretation

Fecal excretion of zinc is the dominant route of elimination. Renal excretion is a minor, secondary elimination pathway. Normal daily excretion of zinc in the urine is in the range of 89 to 910 mcg/g creatinine.

 

High urine zinc associated with low serum zinc may be caused by hepatic cirrhosis, neoplastic disease, or increased catabolism.

 

High urine zinc with normal or elevated serum zinc indicates a large dietary source, usually in the form of high-dose vitamins.

 

Low urine zinc with low serum zinc may be caused by dietary deficiency or loss through exudation common in burn patients and those with gastrointestinal losses.

Day(s) Performed

Monday, Thursday

Report Available

2 to 5 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

84630

82570

LOINC Code Information

Test ID Test Order Name Order LOINC Value
ZNUCR Zinc/Creat Ratio, Random, U 13473-4

 

Result ID Test Result Name Result LOINC Value
615260 Zinc/Creat Ratio, U 13473-4
CRETR Creatinine, Random, U 2161-8